Vitamin B6, or pyridoxine, is a component of the vitamin B complex and necessary for optimal health. In its active form, pyridoxal 5-phosphate (PLP), vitamin B6 is a cofactor in more than 160 enzyme-driven reactions in the body that affect amino acid transformation, synthesis and breakdown of neurotransmitters, cellular energy production and use, immune function, methylation and DNA synthesis and repair.1-3
While most people get enough B6 from food sources, some people are B6 deficient.3 Optimal blood levels of PLP may help support cardiovascular and neurological health.3-7 Through its role as a methylator, vitamin B6 (along with B12 and folate) helps maintain homocysteine levels already within the normal range.8 One study noted a connection between vitamin B6 levels, high homocysteine levels and increased mortality.6
Benefits
Multi-benefit health essential
Health Concern
Glucose Management / Blood Sugar
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Dosage and Use |
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Caution
Caution Some people have reported temporary symptoms of peripheral neuropathy (tingling, numbness sensation,decreased sensation to touch or balance difficulties) whentaking vitamin B6 in doses above 300 mg daily, especiallyif the nutrient is taken without other B complex vitamins.This vitamin should not be taken without co-ingestion ofequivalent doses of other B-complex vitamins. Consultyour physician before taking this vitamin if you are takinglevodopa (L-dopa).
